President Trump reluctantly signed a bill Wednesday imposing new U.S. sanctions on Russia over its annexation of Crimea and alleged meddling in the 2016 U.S. election. The bill was approved by a large and veto-proof majority of lawmakers. It also tightens sanctions against North Korea and Iran. In a signing statement accompanying his signature, President Trump called the sanctions bill significantly flawed and said parts of it unconstitutionally restricted his executive powers. At the U.N., Russian Ambassador Vasily Nebenzya denied his country meddled in the U.S. election, and said Russia would be unbowed by the sanctions.

Vasily Nebenzya: “I really wonder: Is there anything in this world today which Russia is not guilty of? Some of U.S. officials were saying that this is a bill that might encourage Russia to cooperate with the United States. To me, that’s a strange sort of encouragement.”

On Twitter, Russian Prime Minister Dmitry Medvedev said Trump’s signature ended hopes of improving U.S.-Russia relations.